Focal Hyperhidrosis Excessive Sweating of Palms Soles and Underarms Causes and Treatment

It often starts quietly. A handshake that feels uncomfortably damp, paper that curls while writing, shoes that feel wet even in mild weather. For many people, the sweating does not match the situation. It happens in cool rooms, during calm moments, or suddenly spikes with stress or anticipation. Over time, this becomes more than a physical issue. Daily tasks take extra effort, and social interactions can feel tense or embarrassing. This pattern is typical of focal hyperhidrosis.

Focal hyperhidrosis is a condition in which sweating is excessive in specific areas of the body, most commonly the palms, soles of the feet, underarms, and sometimes the face. The sweating is not related to body temperature or physical exertion. Instead, it is driven by overactivity of the sympathetic nervous system, which controls sweat glands. The condition often begins in childhood or adolescence and may improve with age, but for some people it remains persistent and disruptive. While it is not dangerous, the impact on quality of life can be significant, and treatment is often worthwhile.

Focal Hyperhidrosis Quick Overview

CategoryDetails
Main featureExcessive sweating in specific areas
Common sitesPalms, soles, underarms, face
Typical triggerEmotional stress or nervous system activity
OnsetChildhood or adolescence
Treatment goalReduce sweating and improve daily comfort

Focal hyperhidrosis affects localized areas rather than the entire body, which helps distinguish it from other causes of excessive sweating.

Causes

FactorHow it contributes
Sympathetic nerve overactivityStimulates sweat glands excessively
Emotional triggersStress or anxiety worsens sweating
Genetic tendencyOften runs in families
Normal sweat glandsGlands are normal but overactivated

The sweat glands themselves are not diseased. Instead, the nerves signaling them are more active than necessary. This is why sweating can occur even without heat or exercise.

Key Symptoms

SymptomCommon description
Palmar sweatingConstantly damp or dripping hands
Plantar sweatingWet feet, sock saturation
Axillary sweatingVisible underarm wetness
Secondary issuesSkin irritation or odor

Pain is uncommon, but prolonged moisture can lead to skin breakdown, irritation, or secondary infection.

Diagnosis Focus

MethodWhat is assessed
Medical historyPattern and onset of sweating
Physical examDistribution of affected areas
Exclusion of causesRuling out systemic illness

Diagnosis is usually based on clinical features and how much sweating interferes with daily life. Sudden onset of generalized sweating may prompt evaluation for other conditions.

Treatment Direction

ApproachPurpose
Topical agentsReduce sweat production locally
IontophoresisEffective for hands and feet
Botulinum toxin injectionsTemporarily blocks nerve signals
Surgical optionsReserved for severe cases

Treatment is typically stepwise. Mild cases may improve with topical therapy, while moderate to severe cases may require device-based or injection treatments. Surgery is considered carefully due to possible side effects.

Warning Signs

SignWhy it matters
Skin inflammationIndicates irritation or dermatitis
Strong odorSuggests bacterial overgrowth
Recurrent infectionsDue to chronic moisture
New generalized sweatingNeeds medical evaluation

Severe skin infection, fever, or sudden widespread sweating should always be assessed promptly.

Real-Life Experience Example

Some students notice excessive hand sweating during exams. Pens slip, paper becomes damp, and anxiety increases, which further worsens sweating. After trying topical treatments without enough relief, iontophoresis is introduced. Over time, sweating becomes more manageable, and confidence during daily activities improves, even though some symptoms persist.

FAQ

Is focal hyperhidrosis inherited?
A family history is common, suggesting a genetic tendency.

Why does sweating cause odor?
Sweat itself is odorless, but bacteria breaking it down create smell.

Are botulinum toxin injections safe?
They are generally considered safe when performed properly, but effects are temporary.

Does surgery cure hyperhidrosis?
Sweating may decrease in treated areas, but compensatory sweating elsewhere can occur.

Should children be treated?
If sweating interferes with school or social life, treatment may be considered.

Do emotional factors matter?
Stress can worsen symptoms, and managing it may help as part of care.

References

Focal hyperhidrosis is not life-threatening, but its effect on daily life can be substantial. When excessive sweating interferes with routine activities or confidence, tailored treatment options can offer meaningful relief and better long-term control.